Teresa Brito-Robinson, PhD.

Senior Staff Scientist

Teresa - Brito-Robinson, PhD.

(574)631-4192

tbritoro@nd.edu

2017–present

Senior Staff Scientist, WM Keck Center for Transgene Research, University of Notre Dame

2012–2017

Research Staff, Department of Chemical and Biomolecular Engineering, University of Notre Dame

2008–2012

Research Analyst, Scientific Methods, Inc., Granger, IN

1999–2000 

Postdoctoral Fellow, WM Keck Center for Transgene Research, University of Notre Dame

1998–1999

Postdoctoral Fellow, Department of Chemistry and Biochemistry, University of Notre Dame

1997

Ph.D., Biochemistry, Department of Chemistry and Biochemistry, University of Notre Dame

1987

Specialization in Biological Sciences, Simon Bolivar University, Caracas, Venezuela

1985

B. S. Biology, Simon Bolivar University, Caracas, Venezuela

 

 

 

Honors & Awards

 

 

2016-2017          Advanced Diagnostics and Therapeutics Discovery Award. University of Notre Dame

 

1991-1996         Searle Fellowship, University of Notre Dame

 

1990-1991         Zham Fellowship, University of Notre Dame

 

1987-1989          CONICIT, Caracas, Venezuela

 

1984-1985          CONICIT, Caracas, Venezuela

 

 

Research Interests

 

I concentrate in studying cellular and molecular mechanisms of hemostasis under pathological conditions and have also collaborated in development of research/diagnostics tools to facilitate tissue imaging for the study of tissue functioning at multicellular level.

 

 

Publications

 

 

Wu Q, Brodskiy PA, Huizar F, Jangula JJ, Narciso C, Levis M, Brito-Robinson T, Zartman J. In vivo relevance of intercellular calcium signaling in Drosophila wing development.  Development. Submitted manuscript 2017 Sep.

 

 

Höök* P, Brito-Robinson* T, Kim O, Narciso C, Goodson HV, Weisel JW, Alber MS Zartman J. Whole blood clot optical clearing for nondestructive 3D imaging and quantitative analysis * Co-first authors. Biomedical Optics Express. 2017 August; 8(8):3671-3686. doi: 10.1364/BOE.8.003671

 

 

Narciso C, Cowdrick KR, Zellmer V, Brito-Robinson T, Brodskiy P, Hoelzle DJ, Zhang S and Zartman J. On-chip three-dimensional tissue histology for microbiopsies. Biomicrofluidics. 2016 Mar 1; 10(2): 021101.1-021101.5 doi: 10.1063/1.4941708

 

 

Burnette M, Brito-Robinson T, Li, J. and Zartman, J. An inverse small molecule screen to design a chemically defined medium supporting long-term growth of Drosophila cell lines. Mol. Biosyst. 2014 Jul 23; 10(10), 2713-2723. doi: 10.1039/C4MB00155A. PMID: 25096480

 

 

Gutierrez LS, Schulman A, Brito-Robinson T, Noria F, Ploplis VA and Castellino FJ. Tumor development is retarded in mice lacking the gene for urokinase-type plasminogen activator or its inhibitor, plasminogen activator inhibitor-1. Cancer Research. 2000 Oct 15; 60(20): 5839-5847. PMID: 11059781

 

 

Miele RG, Nielsen SL, Brito T, Bretthauer RK and Castellino FJ. Glycosylation properties of the Pichia pastoris expressed recombinant kringle 2 domain of tissue-type plasminogen activator. Biothecnol. Appl. Biochem. 1997 April; 25(2): 151-157. doi: 10.1111/j.1470-8744.1997.tb00427.x

 

Davidson DJ, Brito T, Castellino FJ. Biochemical Analysis of N-linked Glycosylation of Human Plasminogen Expressed in a baculovirus-insect cell system and determination of the enzymes necessary for complex oligosaccharide formation. Glycobiology. 1996 Oct 1; 6 (7): 718B2. doi: 10.1093/glycob/6.7.717